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近红外光谱法测定姜黄素-葡甲胺共晶的含量

Peipei YANG,Xiaodong CONG,Baochang CAI

Chinese Journal of Modern Applied Pharmacy（2014）

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Abstract
目的 利用近红外光谱法测定姜黄素-葡甲胺共晶的含量.方法 纯化共晶后,建立紫外分光光度法含量测定的标准曲线,初步估算共晶含量;再进行近红外光谱扫描,用偏最小二乘法建立含量测定模型,并对建立的模型进行验证.结果 建立的姜黄素-葡甲胺共晶校正模型的相关系数(R)、校正均方差(RMSEC)分别为0.999 86,0.466.结论 建立了一种简便、快速、无损的共晶含量测定方法.
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Key words
near infrared spectrum,curcumin-meglumin cocrystal,content determination
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