醋酸曲安奈德局部注射对变应性鼻炎患者血清白介素4和γ干扰素的影响
China Pharmacist(2014)
Abstract
目的:评价醋酸曲安奈德局部注射对变应性鼻炎患者血清白介素4(interleukin-4,IL-4)和Y干扰素(interferon-γ,INF-γ)表达水平的影响.方法:60例变应性鼻炎患者随机分成观察组和对照组各30例,对照组予盐酸西替利嗪片10 mg,po,qd,观察组患者双侧中、下鼻甲黏膜下局部注射醋酸曲安奈德治疗.治疗4周后,检测两组患者血清IL-4、IFN-γ水平,比较两组疗效和药品不良反应.结果:观察组总有效率为93.33%,高于对照组的73.33%,但差异无统计学意义(P>0.05).治疗4周后,观察组IL-4浓度低于对照组(P<0.01),IFN-γ浓度高于对照组(P<0.01).两组均未发现不能耐受的不良反应或严重不良反应.结论:醋酸曲安奈德局部注射治疗变应性鼻炎疗效较佳,能够降低患者血清IL-4水平,并提高血清IFN-γ水平.
MoreKey words
Triamcinolone,acetonide,acetate,Local,injection,Cetirizine,hydrochloride,tablets,Allergic,rhinitis,Interleukin-4,Interferon-γ
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined