新一代血管紧张素受体阻断剂奥美沙坦酯
CHINESE JOURNAL OF NEW DRUGS(2003)
Abstract
奥美沙坦酯是一种新型的血管紧张素Ⅱ受体AT1的阻断剂,是一种前体药物,它通过阻止血管紧张素Ⅱ与AT1受体结合,使血管平滑肌放松,从而使血压降低.临床上用于治疗各种类型的高血压,不良反应较少.综述了奥美沙坦酯的作用机制、药代动力学及临床评价.
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