药物诱导的肺纤维化
WORLD CLINICAL DRUGS（2007）
Abstract
药物诱导的肺损伤呈多样性,以间质性肺炎和纤维化最常见.引起肺损伤的药物主要有细胞毒类、抗生素类、心血管类、非甾体抗炎类和青霉胺类等.药物诱导的肺纤维化可能与氧自由基的释放和多种细胞因子如IL-1β和TNF-α的产生有关.本文对可能诱导肺纤维化的药物及其作用机理进行初步探讨.
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