兰索拉唑联合西沙必利与雷尼替丁联合西沙必利治疗反流性食管炎的疗效比较

ACADEMIC JOURNAL OF GUANGDONG COLLEGE OF PHARMACY（2000）

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Abstract

目的:观察兰索拉唑联合西沙必利与雷尼替丁联合西沙必利治疗反流性食管炎的疗效比较.方法:将反流性食管炎病人108例分为治疗组60例,用兰索拉唑(30 mg 口服,qN 9:00)加西沙必利10 mg(口服,4次/d);对照组48例用雷尼替丁(150 mg 口服,2次/d)加西沙必利(10 mg 口服,4次/d).疗程均为4周.结果:内镜复查治疗组原食道管粘膜病损愈合、好转的总效率为97%,对照组为62%;治疗组胃灼热和反流症状,总有效率分别达93%和92%,而对照组为62%和62%(均P<0.05).结论:兰索拉唑联合西沙必利较雷尼替丁联合西沙必利治疗反流性食管炎效果好.

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