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谷氨酸脱氢酶型先天性高胰岛素血症研究进展

Xinrou CHEN,Benfang RUAN

Pharmacy Today（2020）

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Abstract
谷氨酸脱氢酶(GDH)广泛存在于生物中,对胰岛素分泌至关重要,其活性异常增高是引发谷氨酸脱氢酶型高胰岛素血症的主要原因.患者表现为持续性低血糖,并伴有脑损伤、癫痫等神经性疾病.本文就谷氨酸脱氢酶型高胰岛素血症发病机制、病理模型、诊断和治疗的新进展作如下综述.
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