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3-脱氧-D-甘露-2-辛酮糖酸寡糖的合成研究进展

Liqin ZHUANG, Yu DENG,Zheng ZENG,Qixin LOU,You YANG

Progress in Pharmaceutical Sciences（2020）

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Abstract
3-脱氧-D-甘露-2-辛酮糖酸是一种非哺乳动物来源的高碳糖,普遍存在于细菌的脂多糖和荚膜多糖中,被认为是研发抗菌疫苗和诊断工具的潜在靶标.按照3-脱氧-D-甘露-2-辛酮糖酸给体的类型,综述了3-脱氧-D-甘露-2-辛酮糖酸糖苷化反应的最新进展,着重介绍了这些糖苷化方法在一些代表性的复杂3-脱氧-D-甘露-2-辛酮糖酸寡糖合成中的应用.
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