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用豌豆凝集素分离良恶性肝病α1-抗胰蛋白酶异质体

陈明忠,黄建英

FUJIAN MEDICAL JOURNAL（2005）

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Abstract
甲胎蛋白(AFP)用于原发性肝癌的辅助诊断已有30余年历史,是当前诊断肝癌的"首选标志",但有20%～30%的肝癌病人血清AFP并不升高,需要寻找AFP以外的肿瘤标志物.近年来有学者报道,检测α1-抗胰蛋白酶(AAT)异质体有助于肝癌的诊断,尤其是对AFP浓度正常的肝癌病人[1].我们参考有关文献,采用豌豆凝集素亲和交叉免疫电泳法(PSA-CIAE)检则AAT异质体,现报告如下.
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