白介素11联合地塞米松治疗急性放射性口腔炎的临床观察
Journal of Hunan Normal University (Medical Science)(2013)
Abstract
目的:观察白细胞介素11联合地塞米松治疗急性放射性口腔炎的疗效。方法:将92例放疗过程中出现了三级放射性口腔炎的鼻咽癌患者随机分为试验组和对照组各46例,试验组予以白细胞介素11溶液联合地塞米松溶液交替含漱,对照组则用地塞米松溶液含漱及抗生素静滴,每日对口腔溃疡及疼痛的程度进行评估。结果:试验组的溃疡愈合有效率为93.4%,疼痛减轻的有效率为95.7%,而对照组则为81.4%和84.8%,两组数据有统计学差异。结论:白细胞介素11联合地塞米松含漱治疗放射性口腔炎疗效较好,可减少抗生素的使用。
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Key words
IL-11,DXM,acute radiation-induced oral mucositis,treatment,clinical observation
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