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消瘤丸对小鼠放、化疗后的减毒作用

Mingfang Guo,Xiushu Liu,Yanhua Xie,Yan Yang,Zhanhua Li,Leiming Ren,Guo Liang

JOURNAL OF HEBEI MEDICAL UNIVERSITY（2000）

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Abstract
目的探讨消瘤丸对放、化疗后小鼠造血系统的影响.方法采用环磷酰胺法(化疗)和60Co照射法(放疗)造成白细胞减少,观察消瘤丸对小鼠外周血白细胞数的影响.结果消瘤丸灌胃给药,1次/d,连续2 周,5 g/kg与10 g/kg组可剂量依赖性地改善放、化疗所致小鼠外周血白细胞数减少和骨髓DNA含量降低,并可提高60Co照射所降低的脾表面结节生成单位.结论消瘤丸有减低小鼠放疗和化疗所致造血系统毒性的作用.
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