聚乳酸及聚乙二醇改性聚乳酸体外降解研究
ACTA ACADEMIAE MEDICINAE MILITARIS TERTIAE（2002）
Abstract
目的研究聚乳酸与聚乙二醇改性聚乳酸的体外降解特性.方法采用奥氏粘度计或凝胶层析法(GPC)测定分子量,并考察其重量与形态的变化.结果聚乙二醇改性聚乳酸开始降解的时间早于聚乳酸,而在相同时间内,前者的重量和分子量下降也较后者明显.结论聚乙二醇改性聚乳酸亲水性优于聚乳酸,是较理想的亲水性药物载体材料.
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