Goat milk extracellular vesicles: immuno-modulation effects on porcine monocyte-derived macrophages in vitro (vol 14, 1209898, 2023)

Giulia Franzoni,Samanta Mecocci,Chiara Grazia De Ciucis,Lorena Mura,Filippo Dell'Anno,Susanna Zinellu,Floriana Fruscione,Livia De Paolis,Tania Carta,Antonio G. Anfossi, Silvia Dei Guidici,Elisabetta Chiaradia,Luisa Pascucci,Annalisa Oggiano,Katia Cappelli,Elisabetta Razzuoli

Frontiers in immunology（2023）

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摘要

Overall, our data support a clinical application of these molecules: they polarized macrophages toward an M1-like phenotype, but this activation seemed to be controlled, to prevent potentially pathological over-reaction to stressors.

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关键词

milk extracellular vesicles, pig, macrophages, classical activation, cytokines, toll-like receptors

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