抗人卵细胞膜抗体的制备及其免疫避孕的可能性
ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY（2001）
Abstract
目的:探讨利用人卵细胞膜抗原制备抗受精抗体的可能性.方法:半纯化人卵细胞膜,利用生物素标记监测纯化技术,经小鼠足部皮下注射免疫获得免疫血清后,采用间接免疫荧光标记及共聚焦显微镜检测其特异性,体外受精抑制试验观察其受精抑制能力.结果:获得的免疫血清对人卵细胞具有特异识别能力,其受精抑制作用与浓度呈正相关.结论:利用人卵细胞膜可获得特异的抗受精抗体.
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