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微小核苷酸转基因小鼠导致心脏功能发生改变

高旭,吕延杰,单宏丽, 马宁,孙丽华, 王宁,张莹,杨宝峰

JOURNAL OF HARBIN MEDICAL UNIVERSITY（2010）

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Abstract
本实验室自2006年起,经过3年时间,于2008年成功构建了心肌组织特异表达miR-1、miR-328的转基因模型小鼠,为研究miR-1、miR-328生物学功能及其与心血管疾病发病机制的关系提供了有力的转基因模型.
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