慢性肾脏病患者肠道菌群的变化及影响研究

Chinese General Practice(2018)

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Abstract
正常情况下,肠道菌群与人体处于互利共生状态.慢性肾脏病(CKD)可引起肠道菌群失调、肠道屏障功能受损,导致肠道菌群移位、尿毒症毒素产生过多和全身炎性反应,加速CKD进展.肠道菌群参与CKD发生发展的机制尚不明确,本文就CKD患者肠道菌群的变化及影响做一综述,希望通过调节肠道菌群延缓CKD进展以降低病死率.
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