唑来膦酸影响骨密度效果的系统评价
Medical Recapitulate(2014)
Abstract
目的 系统评价唑来膦酸影响骨密度的临床效果.方法 计算机检索Cochrane Ce4ntral Register of Controlled Trials,OTA,AAOS,High Wire Press,Springer Link,MEDLINE,EMBASE,CINAHL,ISI Web of Science,CNKI,VIP,万方数据库和中国生物医学文献数据库(CBM)并辅以手工检索关于唑来膦酸影响骨密度的随机对照试验(RCT).结果 共纳入7个RCT.3个RCT显示唑来膦酸可增加腰椎骨密度增加率,3个RCT显示唑来膦酸可增加股骨颈骨密度增加率,4个RCT显示唑来膦酸可增加腰椎骨密度.结论 唑来膦酸对增加全身多处骨密度有一定效果.
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