全氟化碳治疗急性肺损伤/急性呼吸窘迫综合征研究进展
National Medical Journal of China(2012)
Abstract
急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)是急性肺损伤(acute lung injury,ALI)的严重阶段,常并发多器官功能衰竭,病死率在50%左右[1-2].近年来,人们不断探索其发病机制及治疗方案[1、3-4].全氟化碳(profluorocarbon,PFC)是一类氟原子取代碳氢化合物中氢原子所得的化合物,常温下为无色透明液体,密度高,表面张力低,在体内不发生分解代谢,携氧能力强.
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