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HP的两种分型与胃十二指肠疾病的关系

Hong-yan LI,Hao WANG,Guo WANG

HAINAN MEDICAL JOURNAL（2005）

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Abstract
目的探讨幽门螺杆菌(HP)的两种分型与胃、十二指肠疾病的关系.方法选取106例经胃镜诊断并经快速尿素酶检查或C14呼气试验检测为阳性的患者.实验组:慢性胃炎、消化性溃疡和胃癌的患者80例;对照组:症状轻微的慢性胃炎的患者(胃镜诊断充血性胃炎)26例,两组均用免疫印迹技术做血清HP分型抗体检测.结果病例组HPI型有69例,对照组仅3例(P＜0.01)两组比较有显著差异.结论HPI型为HP的毒力菌株.它与慢性活动性胃炎、消化性溃疡及胃癌有着密切的关系.
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