青藤碱对类风湿关节炎患者滑膜细胞与炎性细胞黏附作用的研究

肖涟波,欧阳桂林,张新文,何勇,黄正,张永立,解骏,张秋玉,沈佰华,王利,李宁丽

CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY（2010）

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Abstract

类风湿关节炎(RA)是一种以关节慢性滑膜炎症为特征的全身性自身免疫疾病~([1]).缓解疼痛,减轻关节病理损害,延缓关节畸形变是治疗的主要目标~([2]).青藤碱(sinomenine)是从中药青风藤中提取的生物碱单体,具有显著的镇痛和消炎作用,其盐酸盐制剂临床上用来治疗类风湿关节炎,并取得较好疗效~([3-4]).

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