青藤碱对类风湿关节炎患者滑膜细胞与炎性细胞黏附作用的研究
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY(2010)
Abstract
类风湿关节炎(RA)是一种以关节慢性滑膜炎症为特征的全身性自身免疫疾病~([1]).缓解疼痛,减轻关节病理损害,延缓关节畸形变是治疗的主要目标~([2]).青藤碱(sinomenine)是从中药青风藤中提取的生物碱单体,具有显著的镇痛和消炎作用,其盐酸盐制剂临床上用来治疗类风湿关节炎,并取得较好疗效~([3-4]).
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