Runx2在乳腺癌中作用的研究进展

Tianjin Medical Journal(2014)

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Abstract
Runx2是转录因子RUNXX家族成员之一,其作为参与乳腺组织中某些基因表达调控的重要因子之一,在乳腺上皮细胞分化过程中发挥重要作用,并与乳腺肿瘤细胞株的侵袭性密切相关。Runx2的过表达还与乳腺癌的某些特征相关。本文就Runx2在乳腺癌中作用的相关研究进展综述如下。
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