柔性脂质体研究进展
Journal of Chinese Physician(2014)
Abstract
脂质体(1 iposomes)是新一代的靶向药物载体,具有使药物靶向网状内皮系统、长药效、降低药物毒性、提高疗效、避免耐受性、改变给药途径等优点,特别是近年来脂质体作为基因转移的有效载体,具有病毒类载体无法比拟的优点,因而受到医药界的广泛关注.但脂质体作为药物载体仍存在对有些疾病的靶向特征不理想、体内稳定性和贮存稳定性欠佳等缺点,因而限制了脂质体的临床应用和工业化生产[1].
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