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卡马西平致中毒性表皮坏死松解症1例

包玉双,王春艳,罗艳君

Heilongjiang Medicine And Pharmacy（2015）

Cited 0|Views12
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Abstract
患者男性,15岁,学生.因发热、皮肤瘙痒2d,皮疹1d入院.患者12年前诊断为癫痫病,偶尔发作未接受药物治疗,因近2个月癫痫发作繁频于入院前16d开始口服卡马西平治疗,每次0.2g,每日2次,口服卡马西平第15天时出现发热、皮肤瘙痒,次日前胸及后背出现弥漫性暗红色斑丘疹,且迅速扩散至全身,部分斑丘疹上出现水疱伴疼痛.口唇、口腔黏膜、舌糜烂,吞咽困难.否认既往有药物及食物过敏史.
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