LncRNA-HOTAIR对脓毒症疾病的临床诊断价值
Modern Practical Medicine（2020）
Abstract
目的 分析lncRNA-HOTAIR对脓毒症疾病的临床诊断价值.方法 选择脓毒症患者71例为观察组,同期选取71例健康体检者为对照组,采用实时定量PCR方法检测患者血清中lncRNA-HOTAIR的表达水平,分析lncRNA-HOTAIR与PCT对脓毒症的诊断结果,对比两种诊断方式的灵敏度、特异度及诊断准确率.结果 观察组lncRNA-HOTAIR的相对表达量明显高于对照组;lncRNA-HOTAIR对脓毒症疾病诊断的敏感度、特异度及诊断准确率均高于PCT(均P＜0.05).结论 脓毒症疾病患者lncRNA-HOTAIR水平呈现明显的升高,其可指导临床合理制定治疗方法.
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