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SAPHO综合征患者合并重性抑郁障碍的危险因素

段艳平, 卢洁,洪霞,张伟宏,李忱,姜忆南

Medical Journal of Peking Union Medical College Hospital（2018）

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Abstract
SAPHO( synovitis, acne, pustulosis, hyperostosis, osteitis) 综合征即滑膜炎、 痤疮、 脓疱疮、 骨肥厚、骨炎综合征, 是一种反复损害骨、 关节和皮肤的疾病, 1987年由法国免疫学家Chamot[1]首次提出, 病因不明, 存在细菌学、 免疫学和遗传学等病因假设[2] ,也可能与应激相关[ 3-4].
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