文拉法新与洛哌丁胺联用治疗腹泻型肠易激综合征31例疗效观察

ZHEJIANG PRACTICAL MEDICINE（2005）

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Abstract

目的观察文拉法新与洛哌丁胺联用治疗腹泻型肠易激综合征(IBS)的疗效与不良反应.方法58例伴有情绪障碍的腹泻型IBS病人随机分为治疗组和对照组,两组均用洛哌丁胺2～4mg,治疗组同时加用文拉法新75～175mg,疗程均为6周.结果治疗组第4周、6周末的有效率为87.10%,96.77%;对照组为48.15%,62.96%,两组比较有显著性差异.结论文拉法新与洛哌丁胺联用治疗腹泻型肠易激综合征有较好效果,不良反应轻.

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