格拉司琼在恶性肿瘤化疗中预防消化道反应的临床疗效观察
CHINESE JOURNAL OF TRADITIONAL AND WESTERN MEDICINE(2003)
Abstract
目的探讨格拉司琼预防化疗所致消化道反应的临床效果.方法 40例恶性肿瘤患者,化疗当天及第2~5天每日静滴格拉司琼3mg 1次.结果用格拉司琼后在化疗第1~5天无恶心和轻度恶心的患者在62.5%~82.5%之间,对急性呕吐的有效率达92.5%,对迟发性呕吐有效率在82.5%~97.5%之间.结论格拉司琼对减轻化疗药物所致的恶心反应、对控制急性呕吐及迟发性呕吐疗效与恩丹西酮相当,明显优于胃复安,且副作用小,是一种安全有效的止呕药.
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