VKORC1和CYP2C9基因多态性指导华法林抗凝治疗
World Latest Medicine Information(2020)
Abstract
VKORC1和CYP2C9单核苷酸变异明确影响华法林剂量.本文概括介绍了VKORC1和CYP2C9基因影响华法林剂量的机制、VKORC1和CYP2C9基因多态性与华法林剂量的关系、VKORC1和CYP2C9基因多态性指导华法林的安全性,希望帮助临床医生对VKORC1和CYP2C9基因多态性指导华法林抗凝治疗有一个更清晰的认识,进而帮助临床医生更安全的使用华法林.
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