Propofol effects on cerebellar long-term depression

Neuroscience Letters(2015)

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摘要
•The effect of propofol was studied in cerebellar parallel fiber-Purkinje cell synapses.•Propofol impaired cerebellar long-term synaptic plastcitiy.•Propofol suppressed mGluR1 activity in cerebellar Purkinje cells.
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关键词
aCSF,DHPG,DMSO,GABAA,LTD,LTP,mGlyRl,PC,PF,AMPA,PKC,D-Ser,GluD2,TRPC
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