Anti Leukemic T Cells in Myeloid Neoplasia: Abnormal Cytokine Secretion Patterns May Prevent Immunological Detection and Possibly Reflect Functional Impairment.
Blood(2006)
Abstract
T cells recognising leukemia-associated antigens are present in the T cell repertoire of a subgroup of patients with AML and CML. Difficulties in the detection of such leukemia-reactive T cells in peripheral blood samples of patients are mainly attributed to the low frequency of leukemia-specific T cells.
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