山慈菇提取液对小鼠4T1乳腺癌细胞抑制作用机制的研究
Hubei Agricultural Sciences（2016）
Abstract
探索山慈菇提取液对小鼠4T1细胞抑制作用机制.采用水煎法制备山慈菇提取液,MTT比色法检测小鼠4T1细胞的增殖活性,AnnexinV/PI双染流式细胞术(FCM)检测细胞凋亡.结果表明,山慈菇提取液对4T1细胞有明显的增殖抑制作用(P＜0.05),并呈剂量依赖关系.山慈菇提取液诱导小鼠4T1细胞凋亡效果明显,并有剂量依赖性.山慈菇提取液对小鼠乳腺癌细胞有明显的增殖抑制和诱导其细胞凋亡的作用.
MoreKey words
Shancigu,4T1 cell,proliferation inhibition,apoptosis
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