Multi-Modal Peripheral Nerve Active Probe And Microstimulator With On-Chip Dual-Coil Power/Data Transmission And 64 2nd-Order Opamp-Less Delta Sigma Adcs

The peripheral nervous system (PNS) enables communication between the central nervous system and various organs, for example by conveying sensory information and relaying motor commands. Electrical stimulation of peripheral nerves has been shown effective in treating major intractable disorders ranging from autoimmune disorder to chronic pain. It acts on specific nerves and avoids significant side effects of most drugs. Closed-loop PNS neurostimulators offer the additional benefits of personalization and optimality of the treatment. Such medical devices infer physiological function from measurable nerve action potentials and deliver custom-tailored electrical stimulation to elicit desired clinical outcomes.