Mechanical properties and biocompatibility of 3D printing Ti6Al4V titanium alloy scaffolds

Taking titanium alloy Ti6Al4V porous scaffolds by 3D printing as research object, the relationship between the microstructure characteristics and the mechanical properties was preliminarily investigated. Moreover, the bone marrow mesenchymal stem cells were used to investigate the biological compatibility, and the in vivo bone ingrowth ability of the Ti6Al4V porous scaffolds in a rabbit full-thickness bone defect model was detected. The results show that the mechanical properties of Ti6Al4V porous scaffolds prepared by 3D printing are affected by the porous microstructures with the incipient intensity that is suitable for human body. The Ti6Al4V porous scaffolds also have good biocompatibility and absorbability. The detailed grid structure in Ti6Al4V porous scaffolds provides a unique space for cells to grow, which can increase the proliferative ability of the bone marrow mesenchymal stem cells, and promote the ingrowth speed of the surrounding bone tissue in prosthetic microporous.