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宫颈细胞HPV E6/E7 mRNA检测在宫颈诊断价值中的分析

Linlin Zhao

Journal of Mathematical Medicine（2018）

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Abstract
目的:探讨宫颈细胞HPV E6/E7 mRNA检测在宫颈病变中的诊断价值.方法:选取120例妇产科患者,以组织病理学检查结果为金标准,计算HPV DNA和HPV E6/E7 mRNA的阳性率以及对高级别宫颈病变的诊断效能.结果:高级别病变的HPV E6/E7 mRNA、HPV DNA阳性率均高于慢性宫颈炎(P<0.05),HPV E6/E7 mRNA与HPV DNA检测高级别宫颈病变的特异度有统计学差异(P<0.05).结论:HPV E6/E7 mRNA与宫颈病变的严重程度密切相关,且HPV E6/E7 mRNA检测具有较高的特异度.
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