RAD 51C基因rs 112832782多态位点与卵巢癌易感相关性研究
Medical Journal of Chinese People's Health（2015）
Abstract
目的:对比两组研究对象外周血RAD 51C外显子区SNPs位点差异,寻找卵巢癌发病风险的遗传标记物.方法:将新发卵巢癌患者107例设为观察组,相应医院定期常规体检的健康妇女213例设为对照组.提取两组研究对象外周血全基因组DNA,选择RAD 51C基因外显子区SNPs位点rs112832782和rs 35151472,Primer-blast设计引物,PCR扩增,产物经琼脂糖凝胶电泳检测,达到标准后测序,进行SNP分型,比较两组外周血各型SNP比例是否有显著差异.结果:观察组患者与对照组间rs 112832782差异显著(P＜0.01).结论:RAD 51C基因rs 112832782可以作为卵巢癌易感性的潜在遗传标记物.
MoreAI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined