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脑卒中后抑郁的发病机制及相关因素研究

金永春,金杰,李根龙

MEDICAL JOURNAL OF CHINESE PEOPLE'S HEALTH（2011）

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Abstract
目的:探讨脑卒中后抑郁(PSD)的发生机制与相关因素.方法:对162例脑卒中(卒中组)和140例高血压(对照组)患者用Hamilton量表评定抑郁及其临床特点.结果:卒中组脑卒中抑郁的发生率明显高于对照组(P<0.01).抑郁者BI指数评分(80±5.5)分,非抑郁者(85±6.7)分(P<0.01).抑郁者ESS标准评分(62.13±5.6)分,非抑郁者(70.72±8.9)分(P<0.01).伴语言困难者抑郁发生率高于不伴言语障碍者(P<0.05).结论:PSD的发生与日常生活能力依赖程度及神经功能缺损严重程度有关,伴言语困难者抑郁发生率显著升高.
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