Method for low-radiation-dose lung nodule screening via radiomics technology

user-5f8411ab4c775e9685ff56d3(2018)

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Abstract
The invention discloses a method for low-radiation-dose lung nodule screening via radiomics technology. The method comprises the following steps that (1) a phantom is scanned to obtain scanning data;(2) the scanning data is introduced into radiomics analysis software, a nodule layer is selected, a nodule contour is sketched, and a statistical characteristic based on a histogram, a texture statistic characteristic of a grayscale co-occurrence matrix and a grayscale run texture characteristic of the nodule are calculated; (3) characteristic data is introduced into an R language for statisticalanalysis, and a curve inflection point of each influential factor variable is calculated; (4) the inflection points of all curve variables are integrated to obtain a low-radiation-dose mathematical model of the phantom; and (5) the mathematical model is corrected according to information of an examinee, and low-radiation-dose lung nodule screening is completed. Thus, the ionizing radiation dosageof an examined patient can be reduced, the patient is benefited, higher CT image quality can be obtained while least radiation dosage is received, and requirement of image diagnosis is met.
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Key words
Image quality,Imaging phantom,Grayscale,Histogram,Inflection point,Biomedical engineering,Mathematics,Image diagnosis,Low dose ct,Radiomics
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