β-endorphin and opioid growth factor as biomarkers of physical ability in multiple sclerosis

Chirag Patel,Gary Thomas, Naseem Zomorodi,Ian S Zagon,Patricia J McLaughlin

Multiple Sclerosis and Related Disorders（2021）

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摘要

•OGF levels are elevated in MS patients receiving DMTs.•OGF levels correlate with serum IL-17A and TNF-α levels.•Elevated vitamin D levels correlate with improve 25-ft walking tests.•β-endorphin correlates with better MS-QoL physical composite and social function.

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关键词

Opioid growth factor,β-endorphin,IL-17A,TNFα,MS-QoL54 survey,Vitamin D

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