Cappric Study-Characterization Of Community-Acquired Pneumonia In Spanish Adults Managed In Primary Care Settings
MICROORGANISMS(2021)
摘要
The real burden of community-acquired pneumonia (CAP) in non-hospitalized patients is largely unknown. This is a 3-year prospective, observational study of ambulatory CAP in adults, conducted in 24 Spanish primary care centers between 2016-2019. Sociodemographic and clinical variables of patients with radiographically confirmed CAP were collected. Pneumococcal etiology was assessed using the Binax Now(R) test. Patients were followed up for 10 +/- 3 days. A total of 456 CAP patients were included in the study. Mean age was 56.6 (+/- 17.5) years, 53.5% were female, and 53.9% had >= 1 comorbidity. Average incidence of CAP was 1.2-3.5 cases per 1000 persons per year. Eighteen patients (3.9%) were classified as pneumococcal CAP. Cough was present in 88.1% of patients at diagnosis and fever in 70.8%. Increased pulmonary density (63.3%) and alveolar infiltrates with air bronchogram (16.6%) were the most common radiographic findings. After 14.6 +/- 6.0 days (95% CI = 13.9-15.3), 65.4% of patients had recovered. Hospitalization rate was 2.8%. The most frequently prescribed antibiotics were quinolones (58.7%) and beta-lactams (31.1%). In conclusion, one-third of CAP patients did not fully recover after two weeks of empiric antibiotic therapy and 2.8% required hospitalization, highlighting the significant burden associated with non-hospitalized CAP in Spain.
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关键词
CAP, ambulatory, non-hospitalized, outpatient, pneumococcal CAP, community-acquired pneumonia
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