Composite manual bile duct and preparation method thereof

The invention discloses a composite manual bile duct. A tubular acellular matrix made of a degradable high-molecular polymer material is coated on the inner surface and outer surface of the composite manual bile duct, wherein 2-20 mg of the degradable high-molecular polymer material is uniformly distributed on the inner surface of the acellular matrix for each square centimeter, and 0-20 mg of the degradable high-molecular polymer material is uniformly distributed on the outer surface of the acellular matrix for each square centimeter. The manual bile duct provided by the invention has the advantages of low immunogenicity, good in-vivo repairing effect and good clinical application prospect.