Newcastle disease virus and duck circovirus fusion protein as well as coding gene and application thereof

The invention discloses newcastle disease virus (NDV) and duck circovirus (DuCV) fusion protein as well as a coding gene and application thereof. The fusion protein provided by the invention sequentially contains F protein of duck source newcastle disease virus and Cap protein of duck circovirus from an amino terminal to a carboxyl terminal; the amino acid sequence of the F protein of the duck source newcastle disease virus is the 1st to 553rd bits of a sequence 1 in a sequence table; the amino acid sequence of the Cap protein of the duck circovirus is the 574th to 829th bits of the sequence 1 in the sequence table. According to the invention, a Cap gene of the duck circovirus and an F gene of a duck source NDV isolate are used for constructing a fusion expression recombinant eukaryotic plasmid pcDNA3.1-F-Cap for the first time, the fusion expression recombinant eukaryotic plasmid pcDNA3.1-F-Cap is used as a DNA vaccine to immune SPF ducklings of 2 weeks old, and the result shows that the DNA vaccine can effectively promote the generation of an NDV antibody and a DuCV antibody by the SPF ducklings. The invention provides a theoretical and practical basis for researching a gene vaccine of DuCV and duck source NDV.