Genomic and immunological features of microsatellite instability in colon cancer
Gene(2021)
Abstract
•Microsatellite instability patients showed overexpressed immune checkpoints.•Microsatellite instability patients showed reduced copy number loss of TYMS.•Different mutation condition was found in microsatellite instability patients.
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Key words
MSI,MSS,5-FU,TCGA,ICIs,TILs,TYMS,TLSs,TFH,CYT,DFS,OS
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