Diagnostic Value Of Endobronchial Ultrasound Combined With Rapid On-Site Evaluation Of Transbronchial Lung Biopsy For Peripheral Pulmonary Lesions

AbstracBackground Rapid on-site evaluation (ROSE) has the potential to increase endobronchial ultrasound (EBUS) guide transbronchial lung biopsy (TBLB) accuracy in the diagnosis of peripheral pulmonary lesions (PPLs). However, studies have reported controversial results. The aim of the study was to evaluate the diagnostic value of EBUS-TBLB combination with ROSE in PPLs.Methods A total of 152 patients with PPLs underwent EBUS were enrolled and completed this study. Patients were divided into EBUS combined with ROSE group (EBUS+ROSE group) and EBUS group (EBUS group). The diagnostic yield, operation time, and complications were compared between the two groups.Results The diagnostic yield in EBUS+ROSE group was 85.9%, the operation time was (24.6 +/- 6.8) min, the diagnostic yield in EBUS group was 70.3%, and the operative time was (32.4 +/- 8.7) min, there were significant differences in diagnostic yield (chi(2) = 5.456, P = .016) and operation time (t = 3.167, P = .001) between the two groups. No severe procedure related complications were observed, such as, pneumothorax and hemorrhage.Conclusions ROSE can improve the diagnostic yield and shorten the operation time. EBUS combined with ROSE is an effective diagnostic method for PPLs.