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Lytic Bone Lesion: An Unusual Presentation Of Hairy Cell Leukemia

CUREUS(2021)

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Abstract
Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United Stales. WI generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic al the Lime of diagnosis. Treatment is reserved for those with anemia, thrombmytopenia, neutropenia, recurrent infections, symptomatic splenomegaly, or lymphadenopathy impairing vital organ function. Purine analogs are the mainstay of treatment with a durable response. We report a case of a 49-year old Ukrainian male who presented with bone pain secondary to a lytic hone lesion who was diagnosed with HCL.
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Key words
hairy cell leukemia, massive splenomegaly, cladribine, moxetumomab pasudotox, rituximab
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