Radiation-Chemical Biotechnology for Producing Ultrashort (50-100n) Single-Chain Polydeoxyribonucleotides with Anticancer Activity

S. V. Stovbun,A. S. Vedenkin,M. G. Mikhaleva,A. A. Bukhvostov,D. A. Kuznetsov

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE（2021）

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摘要

The fundamental possibility of obtaining ultrashort (50n-100n) single-stranded polydeoxyribonucleotides by the method of radiation-chemical destruction of total yeast DNA was established and their anticancer activity was shown.

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关键词

polydeoxyribonucleotides, DNA, radiation-chemical destruction, MTT test, cytotoxicity

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