Role of ferroptosis in neurological diseases
Neuroscience Letters(2021)
Abstract
•Ferroptosis is a nonapoptotic regulated cell death characterized by iron-dependent accumulation of lipid peroxides.•Ferroptosis plays a crucial regulatory role in the pathology of neurological diseases.•Inhibition or activation of ferroptosis provides a promising therapeutic modality of neuroprotection.
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Key words
Neurological diseases,Ferroptosis,Iron,Lipid peroxide,Polyunsaturated fatty acids,Nervous system
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