Antifungal activity of Swietenia humilis (Meliaceae: Sapindales) seed extracts against Curvularia eragrostidis (Ascomycota: Dothideomycetes)

The mycelial growth inhibition (MGI) of Curvularia eragrostidis by Swietenia humilis seeds extracts (hexane, ethyl acetate, dichloromethane and methanol) at four concentrations (250, 500, 1000 and 2000 ppm) was evaluated. The daily mycelial growth (DMGR), MGI and median effective concentration (EC50) were determined. The DMGR and MGI were significantly affected (p < 0.05) by crude extracts concentrations. The ethyl acetate precipitate (EtOAcp) at the highest concentration (500 ppm) achieved the lowest DMGR (2.54 mm/day, p < 0.05) against the control (9.96 mm/day). Moreover, EtOAcp (500 ppm) significantly increased the MGI% of C. eragrostidis (p < 0.05) by 68.2%, resulting to be the most inhibitory extract by its low EC50 (729 ppm). The medium polarity extracts of S. humilis (EtOAcp) could be considered for future studies on antifungal activity against phytopathogens.