Genetic characterization of acute myeloid leukemia patients with mutations in IDH1/2 genes

Leukemia Research（2021）

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摘要

•IDH1/2 cases account for 23% of the studied cohort.•Mutual exclusivity was confirmed for IDH1 and IDH2 mutations.•IDH1 (86%) and IDH2 (89%) mutations frequently constitute an ancestral event.

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