Association of plasma cell-free DNA with survival in patients with IDH wild-type glioblastoma.

Stephen J Bagley,Jacob Till,Aseel Abdalla,Hareena K Sangha,Stephanie S Yee,Jake Freedman,Taylor A Black,Jasmin Hussain,Zev A Binder,Steven Brem,Arati S Desai,Donald M O'Rourke,Qi Long,Seyed Ali Nabavizadeh,Erica L Carpenter

Neuro-oncology advances（2021）

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摘要

cfDNA concentration is a promising prognostic biomarker for patients with wild-type GBM. Plasma cfDNA can be obtained noninvasively and may enable more accurate estimates of survival and effective clinical trial stratification.

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关键词

cell-free DNA,glioblastoma,liquid biopsy,overall survival,progression-free survival

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