Incidence and risk factors for preneoplastic and neoplastic lesions of the colon and rectum in patients under 50 referred for colonoscopy

Simona Agazzi,Marco Vincenzo Lenti,Catherine Klersy,Elena Strada,Lodovica Pozzi,Laura Rovedatti,Marco Bardone,Aurelio Mauro,Martina Costetti,Stefania Costa,Federico De Grazia,Antonio Di Sabatino

European Journal of Internal Medicine（2021）

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摘要

•Out of 1778 patients <50 years old undergoing colonoscopy, 27 (1.5%) had colorectal cancer•13/27 (48%) colorectal cancer patients had a metastatic disease at the time of diagnosis•Patients aged 40-50 years old had a greater risk compared to those aged <40•The presence of alarm symptoms was associated with a diagnosis of colorectal cancer (OR 3.7; p=0.005)

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adenoma,alarm symptoms,colorectal cancer,screening Abbreviations BBPS, Boston Bowel Preparation Scale,CRC, colorectal cancer,eoCRC, early-onset colorectal cancer,IBD, inflammatory bowel disease,IQR, interquartile range,OR, odds ratio,SD, standard deviation

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