Ghrelin treatment leads to dendritic spine remodeling in hippocampal neurons and increases the expression of specific BDNF-mRNA species

M.L. Perea Vega,M.S. Sanchez,G. Fernández,M.G. Paglini,M. Martin,S.R. de Barioglio

Neurobiology of Learning and Memory（2021）

引用 6|浏览5

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摘要

•Gr increases DS density in cultured hippocampal neurons.•Gr increases DS density in hippocampus (Hp) after “in vivo” icv administration.•The increase in DS density is accompanied by changes in spine morphology.•Gr enhances the expression of specific BDNF-mRNA species in Hp.

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关键词

Ghrelin,BDNF-mRNA,Dendritic spines,Synaptic plasticity

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